Cetirizine,又称西替利嗪,羟嗪的衍生物,是可口服的H1受体拮抗剂,不易透过血脑屏障,能抑制组胺引起的毛细血管扩张和通透性增加,临床上用于治疗慢性荨麻疹、哮喘等。
参考文献
[1] Spencer CM, Faulds D, Peters DH. Cetirizine. A reappraisal of its pharmacological properties and therapeutic use in selected allergic disorders. Drugs. 1993 Dec;46(6):1055-80. doi: 10.2165/00003495-199346060-00008(IF:4.993).
[2] Shih MY, Hsu JY, Weng YS, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. doi: 10.2500/aap.2008.29.3156(IF:2.124).
[3] Shimizu T, Nishihira J, Watanabe H, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9. doi: 10.1111/j.1365-2222.2004.01836.x(IF:4.741).
-25~-15℃保存,有效期3年。