The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The EGFR subfamily of receptor tyrosine kinases comprises four members: EGFR, HER2 , HER3 and HER4 . Within the ECD, human EGFR shares 88% aa sequence identity with mouse and rat EGFR. EGFR binds a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, and epigen. EGFR signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis.

高纯度、高活性、低内毒素、高批间一致性

-25 ~ -15℃保存，收到货之后有效期1年。 复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。