Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

稀释比WB: 1/1000

产品数据

Western blot
	Western blot analysis of Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) in EGF treated A549 and Hydroxyurea treated NIH/3T3 lysates, using Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody（right）and p44/42 MAPK (Erk1/2) antibody (left).

冰袋运输，-20℃保存。