(R)-Lisofylline ((R)-Lisophylline)是一种己酮可可碱代谢物的(R)-型对映体，是具有生物活性的异构体。(R)-Lisofylline表现出抗炎活性，也是一种溶血磷脂酸酰基转移酶抑制剂，可减少不饱和磷脂酸物质的产生。(R)-Lisofylline在动物体内的药代动力学数据良好，可用于I型糖尿病。

参考文献

1.J J Bright, et al. Prevention of Experimental Allergic Encephalomyelitis via Inhibition of IL-12 Signaling and IL-12-mediated Th1 Differentiation: An Effect of the Novel Anti-Inflammatory Drug Lisofylline. J Immunol. 1998 Dec 15;161(12):7015-22.

2.D Bleich, et al. Lisofylline, an inhibitor of unsaturated phosphatidic acid generation, ameliorates interleukin-1 beta-induced dysfunction in cultured rat islets. Endocrinology. 1996 Nov;137(11):4871-7.

3.Yang ZD, et al. The anti-inflammatory compound lisofylline prevents Type I diabetes in non-obese diabetic mice. Diabetologia. 2002 Sep;45(9):1307-14.

4.Elżbieta Wyska, et al. Physiologically Based Modeling of Lisofylline Pharmacokinetics Following Intravenous Administration in Mice. Eur J Drug Metab Pharmacokinet. 2016 Aug;41(4):403-12.

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